Liver-gut axis controls the colonic mucus barrier via hepatic FXR.
Collaborative contribution on imaging analysis of mucus barrier, published in J Hep Reports. Congrats to all and thanks to Noortje Ijssennagger and Saskia van Mil for the fun collaboration!
Ijssennagger et al., J Hep Reports 2021
MATISSE method single-cell spatial analysis out now
May 11th our novel method for IMC& microscopy analysis “MATISSE” has been published. This team-effort spearheaded by Matthijs Baars allows high-quality single-cell analysis in tissue. The paper is open-access and contains a manual, with all scripts and data available. Updated with publisher correction for Fig 1A.
Artist: Matthijs J.D. Baars
Launch multidisciplinary project Structures of Strength
Center for Unusual collaborations has funded it’s first collaborative projects, allowing unusual multidisciplinary teams to tackle big societal problems. Yvonne is amongst the first group of CUCo fellows, and will contribute to the development of a novel platform Structures of Strength.
‘T cells lose GRP in autoimmunity’ story out in Eur J Immunology!
Congrats to the lab, first author Matthijs, and our amazing collaborators! Thanks EJI for a nice highlight ‘In this issue’ :T cells lose GRP in autoimmunity’. We show a novel regulatory mechanism of RasGRP1 expression that underlies autoimmunity. Read more here.
Should research balance curiosity with societal impact?
Yvonne Vercoulen , Assistant Professor at the Center for Molecular Medicine in the University Medical Center Utrecht, discusses the importance of curiosity-driven, fundamental research in the first blog of the Utrecht Young Academy.
RASGRP1 story Matthijs published.
Congrats to the lab and our amazing collaborators! In short: we describe a novel regulatory mechanism of RasGRP1 expression that underlies autoimmunity. Read more here.